MOOSE (Meta-analysis Of Observational Studies in Epidemiology) provides reporting guidance for meta-analyses of observational studies.

Standardize reporting when pooling observational epidemiological studies.

Who should use it

Epidemiologists conducting observational meta-analyses.

Recommended for meta-analyses of observational studies.

• Background and objectives
• Search strategy
• Inclusion criteria
• Data extraction
• Statistical methods
• Results and bias assessment

• Observational study eligibility defined
• Heterogeneity and bias explored
• Effect measure justification

• Pooling incompatible designs
• Ignoring publication bias
• Missing heterogeneity assessment